Wisert was an American football and baseball player. He played college football and college baseball at the University of Michigan. Wistert was the first of the three Wistert brothers–he was succeeded by Albert (Al) and Alvin–who were named All-American tackles at Michigan and later inducted into the College Football Hall of Fame. He was elected to the College Football Hall of Fame in 1967.
During his time at Michigan, Wistert played on three consecutive Big Ten Conference football championships teams, including two that won back-to-back national championships. He was also Big Ten Conference MVP in baseball in college and later played for Major League Baseball’s Cincinnati Reds.
The Wistert brothers all wore jersey No. 11 at Michigan and are among the seven players who have had their numbers retired by the Michigan Wolverines football program.